The new funding phase (2019-2025) will employ nine people directly and includes 68 academic investigators across nine partner institutions. The new advanced research programme covers the full scope of pharmaceutical R&D with the exception of the discovery of new chemical entities under five research themes (PharM5), Molecules, Materials, Medicines, Manufacturing and Modelling with leading academic experts.
Moleclules 1: New methodologies for the asymmetric synthesis of existing APIs & future drug candidates. Molecules II: Develop molecules & methods for automated & in flow generation of targeted drug hybrids. Molecules III: Rapid initial toxicity & biological efficacy testing: new chemical entities, combinations and formulations.
Materials: Advance our understanding of SCCMs & MCCMs in order to enable improved orally delivered drug products.
Medicines: Optimise the development, production & use of safe & effective medicines.
Manufacturing: Enabling a disruptive change in the manufacture of drug substances and drug products.
Modelling: New techniques to design and predict behaviour in silico in order to reduce trial-and-error experimentation.
SSPC is hosted by the University of Limerick based at the Bernal Institute in partnership with University College Cork, National University of Galway, Trinity College Dublin, Dublin City University, University College Dublin, Royal College of Surgeons Ireland, Maynooth University and Waterford IT.