Our People » Kieran McGourty

Office: AD3-019,
Analog Devices Building,
University of Limerick.

+353 61 237755



Ph.D. in Biological Engineering

Research and Teaching Interests

Stem cell differentiation
Stem cell niche
Extracellular matrix biology
Cell cycle
Intracellular trafficking
Cell signalling
Infection and immunity
Proteomics, transcriptomics, pathway analysis
Microscopy, especially high throughput imaging and confocal microscopy

Kieran McGourty

Kieran McGourty is currently a lecturer below the bar in the Chemical Sciences department at the University of Limerick (UL).  Kieran undertook his undergraduate studies at UL, in Industrial Biochemistry, where he worked with Dr. Jakki Cooney and Dr. Todd Kagawa.  In 2006, motivated by these experiences, he went on to attain a Wellcome Trust funded PhD working with Prof. David Holden FRS, Imperial College London, studying the molecular basis of infection. During this time, Kieran published several high impact papers on the intracellular interaction of Salmonella Typhimurium with the host before changing field from cellular microbiology to cell biology.  Kieran took a post-doctoral research position in 2012 with Dr. Emmanuel Boucrot at University College London (UCL), with a primary research focus on the cell cycle and extracellular matrix (ECM) biology.  Kieran’s work here resulted in an extensive study into how ECM interaction evoke specific intracellular signalling profiles in quiescent cells. These findings are currently in preparation for publication.

Kieran’s research aims to understand the signals that govern cell behaviour in the niche, especially the intestinal, muscular and epidermal niche.  Kieran employs a number of high-throughput techniques to achieve this including; transcriptomics, phosphoproteomics, antibody signalling protein arrays and high content imaging, in addition to standard biochemical techniques.

• Full Biography & Research Statement

Additional Links

• LinkedIn Profile
• Google Scholar Publications
• Twitter – @kieranmcgourty
• Twitter – @biosciber

Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies
H Augustin, K McGourty, MJ Allen, SK Madem, J Adcott, F Kerr, CT Wong, …
PLoS biology 15 (9), e2001655
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Myostatin-like proteins regulate synaptic function and neuronal morphology
H Augustin, K McGourty, JR Steinert, HM Cochemé, J Adcott, …
Development, dev. 152975
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Salmonella inhibits retrograde trafficking of mannose-6-phosphate receptors and lysosome function
K McGourty, TL Thurston, SA Matthews, L Pinaud, LJ Mota, DW Holden
Science 338 (6109), 963-967
• View Journal Article