Friday, 13 November 14:00
The speaker will be Prof. Rainer Fischer a Presidential Fellow and Research Professor at Purdue University
The title of his webinar is: Plant and yeast derived malaria vaccines
The development of recombinant antibodies and vaccines has allowed us to treat and prevent a large number of life-threatening diseases. However, as things stand in late 2020, the speed, capacity and scalability of current production systems is beginning to place limitations on this crucial technology. The large-scale production of antibodies, vaccines and other pharmaceutical recombinant proteins is restricted by the industry’s current reliance on fermenter technology, particularly the culture of mammalian cells. This expensive and time-consuming production platform is preventing the distribution of recombinant protein drugs to those most in need. One way in which the above limitations can be addressed is through the use of plants and plant-based expression systems for rapid recombinant pharmaceutical protein production. We have also developed an interesting multi-stage malaria vaccine and neutralizing rabies antibody candidates and will discuss how these products have matured over the years both in performance and in manufacturing with the aim in mind to bring these two products into translational research within the next months.
Finally state of the art technology developments to accelerate the development and production of PMPs as well as regulatory issues will be discussed. Along this line an innovative new manufacturing concept using LED lighting in a vertical farm concept have been developed
About the Presenter
Rainer Fischer, Ph.D., was named Senior Executive for Innovation and Discovery in April 2019. Fischer joined the The Indiana Biosciences Research Institute (IBRI) in April of 2017 as the Chief Scientific and Innovation Officer. In October that same year, he also was named Chief Executive Officer. Fischer spent 19 years building and leading the Fraunhofer Institute for Molecular Biology and Applied Ecology (IME) in Aachen, Schmallenberg, Muenster, Giessen, Frankfurt and Hamburg in Germany, and its subsidiaries in Newark, Delaware, USA and Santiago, Chile. The Fraunhofer-Gesellschaft is the largest applied science research organization in Europe, with applied research aimed at addressing issues of health, security, production technology, energy, materials, and the environment.