Friday, 20 September 12h00 MSG-025 Bernal Institute

Seeded Granulation


Seeded granulation was firstly introduced by Rahmanian et al. (2011) and is a process of making granules with uniform properties and structure. This occurs when small particles form around a larger core particle and forms a core-shell (seed) structure. The process has applications in the pharmaceutical industry as it allows for even drug distribution through the granules as a seeded granule should be covered in one full layer of the fine particles. This presentation introduces ‘seeded granulation’ and how it was discovered and the effect of various batch and continuous granulators in formation of seeded granules as well as the current regime map for production of seeded structure. The process has also come to much attention of local and international pharmaceutical companies in UK and overseas.


Nejat Rahmanian has over 23 years’ experience in both academia and industry. In industry, he worked with international oil and gas companies, Shell, PETRONAS, NIOC and TOTAL for the development of the South Pars Gas, the largest gas‐condensate reservoir in the world. He has been a member of academic staff in Chemical Engineering at the University of Bradford since 2013, shortly after the re‐launch of the department in 2010 and prior to this was Senior lecturer in Chemical Engineering at Petronas University, Malaysia. He has also been MSc programme leader for Chemical and Petroleum Engineering since 2015. He undertook his PhD in Chemical Engineering at the University of Leeds and received his doctoral degree in Particle Technology in 2009, working on a major EPSRC‐sponsored research project in collaboration with Pfizer, P & G, Borax Europe Ltd and Hosokawa Micron BV (The Netherlands). He is an active researcher with current interest in energy, carbon capture and particle technology. He has developed a novel process in granulation technology, `seeded granulation’, used for the production of uniform granule properties. This new process is attracting much attention from large pharma companies, currently Novartis Pharma Ltd and two other UK pharma companies.


He is actively involved in organising events for the wider chemical engineering society, an elected member of the Committee of the IChemE Particle Technology Subject Group, a member of the UK Carbon Capture and Storage (UKCCS) Group and a member of the Institute of Materials, Minerals and Mining (IOM3). Within the University he is a member of the Faculty Board and the PGR Committee.

Tea/coffee will be available at 11h45

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