A new drug product that combines multiple anti-inflammatory steroids in a single crystalline and stable material is described in the recent journal article published in IUCrJ. This research challenges old beliefs that such phase could not be possible. From a practical point of view the paper shows the potential to make drugs that are more easily administered with fewer sides effects.
Read the full paper here; Cortisone and cortisol break hydrogen-bonding rules to make a drug–prodrug solid solution
Vivek Verma,a Simone Bordignon,b Michele R. Chierotti,b Monica Lestari,a Kieran Lyons,a Luis Padrela,a Kevin M. Ryana and Matteo Lusia*
This research was funded by a Science Foundation Ireland Starting Investigator Research Grant and Enterprise Ireland funding.